Kun je kanker in je knie krijgen?

Een osteosarcoom ontstaat in een bot, uit osteoblasten. Osteoblasten zijn cellen die bot maken. Deze cellen zitten in alle botten. Meestal ontstaat een osteosarcoom in je been, vlak boven of onder je knie.

Een osteosarcoom komt meestal voor aan de knie. Bij sommige uitzaaiingen is er extra kalkvorming, bij andere ontstaat er eerder botopslorping en worden de beenderen zeer broos, waardoor ze snel breken. De tumor kan het plooien of strekken van een gewricht moeilijker maken.

What is osteosarcoma?

Osteosarcoma is defined as the primary malignant mesenchymal bone tumor where the malignant tumor cells directly form the osteoid or bone or both.1,2,3,4,5,6,7,8,9,10,11,12Demonstration of osteoid directly formed by the malignant cells in histopathology is essential for making the diagnosis of osteosarcoma.2,3

How is osteosarcoma diagnosed?

To diagnose osteosarcoma, the doctor may begin with a physical exam to better understand the symptoms. Imaging tests help your doctor investigate your bone symptoms, look for cancer and look for signs that the cancer has spread. Imaging tests may include: A biopsy procedure is used to collect a sample of suspicious cells for laboratory testing.

What is the role of biopsy in the diagnosis of sarcoma?

The biopsy confirms the diagnosis and reveals the grade of the tumor. Enneking system for staging malignant musculoskeletal tumors and American Joint Committee on Cancer (AJCC) staging systems are most commonly used for extremity sarcomas. Keywords: Osteosarcoma, imaging, biopsy, Enneking staging

How are osteosarcoma operations done?

Most osteosarcoma operations can be done in a way that removes all of the cancer and spares the limb so that function can be maintained. Whether this procedure is an option depends, in part, on the extent of the cancer and how much muscle and tissue need to be removed. If a section of bone is removed, the surgeon will reconstruct the bone.