Wat is het endoplasmatisch reticulum?

Het endoplasmatisch reticulum (ER) of reticulum endoplasmaticum is een netwerk (reticulum) van membranen dat gelegen is in het cytoplasma van een eukaryote cel. Het bestaat uit twee dicht tegen elkaar liggende membranen waartussen holten en kanalen worden gevormd.

Het endoplasmatisch reticulum, een organel, is een netwerk van buisjes en zakjes in de cel. Het is opgebouwd uit één membraan dat verbonden is met het membraan van de celkern. Het endoplasmatisch reticulum komt alleen voor in eukaryote cellen.

What is endoplasmic reticulum?

Endoplasmic reticulum is a network of membranes inside a cell through which proteins and other molecules move. Proteins are assembled at organelles called ribosomes. When proteins are destined to be part of the cell membrane or exported from the cell, the ribosomes assembling them attach to the endoplasmic reticulum, giving it a rough appearance.

How are stacked endoplasmic reticulum sheets connected?

“Stacked endoplasmic reticulum sheets are connected by helicoidal membrane motifs”. Cell. 154 (2): 285–96. doi: 10.1016/j.cell.2013.06.031. PMC 3767119. PMID 23870120. ^ Guven J, Huber G, Valencia DM (October 2014). “Terasaki spiral ramps in the rough endoplasmic reticulum”. Physical Review Letters. 113 (18): 188101.

What causes the endoplasmic reticulum to become engorged?

Sometimes, when those proteins are made improperly, the proteins stay within the endoplasmic reticulum. They’re retained and the endoplasmic reticulum becomes engorged because it seems to be constipated, in a way, and the proteins don’t get out where they’re suppose to go.

What part of the endoplasmic reticulum is studded with ribosomes?

The outer ( cytosolic) face of the rough endoplasmic reticulum is studded with ribosomes that are the sites of protein synthesis. The rough endoplasmic reticulum is especially prominent in cells such as hepatocytes.